I'm actually not premenopausal. I'm in another group of people who need hormone replacement therapy who have been overlooked. I suffer from Endometriosis, hypo-androgenic PCOS, Addison's Disease, as well as other autoimmune diseases. My hormone producing organs are severely damaged and no longer function properly. Because symptomatic onset started in my mid-20's, and because I was thin, Addison's disease and PCOS were overlooked for over a decade. My health began to deteriorate rapidly at 35 years old. I had been an athlete since I was a child but I always suffered from chronic exhaustion, and by the time I was 35, I could no loner participate in sports. I sought out experts in reproductive endocrinology and adrenal endocrinology. I was deemed infertile, I had no libido, I was depressed, chronically fatigued, suffered from an inability to focus and be productive in work, and I had an atrophied vagina. While my doctors are still fine-tuning the correct dosages of hormones right for my body, hormone replacement therapy has saved my life and my marriage. I've regained some normalcy in every day activities. And, most importantly, hormone replacement therapy, especially for those who are not peri-menopausal, menopausal or post menopausal, and for those who want to live normal, active lives and retain their fertility, tailored, compounded hormone replacement therapy is critical.