Following a full hysterectomy, I had no success with conventional estrogen treatments. My GYN prescribed Estradiol drops, compounded. This was in 1992, and I am still using them today. Since 1992, I have had 2 bad falls and sustained no broken bones. Attending physicians said my bones were in remarkable shape, and attributed it to the Estradiol treatment. I am currently seeing an orthopedic surgeon for hip and low back issues. He tells me my hips are in remarkable shape for my age, 73 years old. Without my Estradiol, I have headaches and lack of energy. They are essential to my daily lifestyle. PLEASE do not take them away from me!