I am 70 years young. I had a full hysterectomy at age 26. I was originally given premarin for hot flashes, night sweats, hair loss etc. After several years on pills had no relief. It was suggested I try bioidentical hormone cream about 30 years ago and I have never looked back. Words are not enough to say how much my mental, emotional and physical health have improved and continue to do so to this day! It would be a tragedy to NOT have these creams compounded by the experts at compounding pharmacies.