I have been on BHRT since 2007 and am very happy with this treatment. I initially started because of a diagnosis of osteoporosis. After this treatment I had another Dexa Scan and my diagnosis was now osteopenia. I feel that this treatment has helped me in many ways. My blood levels are checked every year to make sure I am in balance hormonally. I would much rather use natural replacements rather than treatments like Premarin which I understand comes from pregnant mare's urine, which has components not naturally found in humans.