Once I began applying compounded hormone creams the daily migraines went away, I lost weight (good loss) and I now have more energy. I have MTHFR and I had a total hysterectomy (appendix, cervix removed, and part of my bowels due to endometriosis at age 26). I have difficulty absorbing nutrients due to my health issues, and my hormones were non-existent until I started the compounded hormone creams. I do not take regular HRTs in the form of pills (equine estrogens) due to my delicate system and the potential risk of cardio issues due to the MTHFR I have. If compounded hormones are removed, I will have DAILY migraines, gain unwanted weight, and feel sluggish.