I have done bio-identical hormonal replacement for many years now. I take testosterone pellets and progesterone capsules. Without them I cannot function. I had occasions in which I had to suspect the treatment because of being out of the country around the time the pellets were due, or in another circumstance when I changed doctors and there was a lapse because of scheduling difficulties. The lack of the hormones affect me deeply. Without them I live in constant anxiety, I have no energy to perform daily tasks and no sexual drive. My mood grows darker as time goes by and the levels fall. Hormones are life! My dosage has been tweaked carefully along these years, they vary as I go through peri-menopause. FDA-approved hormones are not customizable and the dosage does not always work for my needs. I love and trust the compounding meds I have used for many years and don’t wish to switch to mass manufactured hormones.