I am hypothyroid for 20 years. I was prescribed Synthroid, then Levothyroxine, and neither improved my symptoms. Then I was prescribed Armor Thyroid, then Natural Thyroid and my symptoms persisted. It wasn't until I was prescribed a compounded prescription of a balanced formula or T3 and T4 - the exact mcg that my body was missing - that my symptoms resolved. I pay a premium for this medication as commercial insurance and Medicare do not cover a clinical compound. But I am willing to pay for a prescription that actually works for me and relieves my hypothyroid symptoms. My Thyroid will not respond to pharmaceutical company artificial formulas.