Started cream in Peri Menopuse due to emotional instability, hot flashes, vaginal dryness and inability to fall asleep or stay asleep. Quality of life was main need. The cream has helped with all of this and has taken me into Menopause with very little issues. I had a friend in the Medical Community who informed me if using hormones it was best to start before Menopause as then less issues with the increase of Cancer concern by some without a “burst” in hormones with Menopause. Don’t let the choice to use compounds be taken away! .