My mother has severe osteoporosis with 75% bone mass loss in her spine early onset in her late 30's. I as well had borderline low bone density in my 30's, which shows improvement and no deterioration. I have used hormone replacement therapy since age 50. With a two year break. During the break I had debilitating inattention and anxiety, as well as obesity with increase in abdominal fat, increased LDL, low HDL horrible Lipid panel, fluid retention and hot flushes, sluggish gallbladder, urinary incontinence, zero libido and exacerbation of eczema, as well as severe insomnia with little sleep. All these symptoms ceased with my return use of bioidentical hormones. My quality of life is so much better. I have tried prescription pharmaceutical synthetic hormones in progesterone and did poorly with the standard dosage as I require very fine adjustments that can only be achieved by compounding my medication. Despite my having to spend my limited income on out of pocket medications, it is worth very penny and I feel like my healthy younger self at now 60. Thank you to my doctor who monitors me closely and to my pharmacy who I can consult at any time. I depend on the custom tailored bioidentical hormones to have a good quality of life.