My experience with compounded HRT has been such a sucess! I have been using them for 17 years. When I started at age 47 years old, I was going through an early menopause due to an autoimmune disease. I had significant osteopenia. Now, at age 65 years old, I am currently stable. The hormones have been essential for the state of my bone health. This has been a miracle for me. They are safe. I have never had any negative side effects, only positive ones. I truly hope that these bioidentical hormones are protected and made available to all who could benefit from their use! This has saved my life!