Menopause caused extreme migraine incidents that occurred every day for a few months. Hormone replacement brought the incidence of migraines back to a manageable level of 7-10 x/mo. I have tried many preventative drugs and botox, none of which were helpful. I recently weaned myself off the hormone replacement only to find that the incidence of migraines returned. As soon as I went back on hormone replacement, migraines were again reduced to a manageable level.