Hello, my name is Roxanne Steiny, and I've been using Bioidentical Progestone cream for two years, and I can honestly say if it weren't for this and my estradiol, I would be on daily anti-depressants at best, worse, I may not be typing this message. I was the woman who was never on birth control and was never going to take hormones. I toughed it out for a couple of years after hitting menopause until my annus horriblis 2 yrs. ago. My husband had chronic health issues, I lost my job, and my closest friend was diagnosed with cancer. I became a full-time caregiver and was crippled by lack of sleep at night, exhaustion during the day and wild mood swings and hot flashes. It was becoming nearly impossible to take care of my friend and husband and finally decided in order to function, I would take estradiol and the accompanying progesterone cream my OBGYN prescribed in order to offset the chance of endometrial cancer. I noticed the benefits within weeks and am grateful beyond measure for the access to compounded progesterone. The quality of my life has allowed me to get back to my baseline prior to menopause and live a full life. Given the challenges and extraordinary times we've now endured with COVID, I was shocked to discover the possibility of taking compounded pharmaceuticals away from millions of people like me. I implore the FDA to consider the benefits that far outweigh any risk and to to allow these critical therapies to continue.