It makes my life so much nicer by being able to adjust the replacement to help with what issues I am having. I have been level for a while now but if I start having night sweats or mood swings, etc. I can call the pharmacy and explain what is going on. With my doctor's approval, I can adjust my dose and it is tailored to my body- not just a dosage prescription for anyone. Also, I am at a higher risk for breast cancer and the hormone cream and progesterone capsules are more natural and there is less risk of breast cancer.