It has been the best thing to happen to me. After my hysterectomy, I was miserable. Moody, depressed, and my skin looked like I was 80, but I was 38. I had terrible migraines on a regular basis. I had ZERO libido. I didn't find bioidentical HRT until several years after my hysterectomy. This truly has saved my marriage and has changed my way of thinking. I am no longer dealing with depression, migraines, my skin is so much better, and needless to say my libido is back!