In 1987 I had a gastric bypass. My thyroid was up and down for years until a holistic doctor figured out that my stomach was not digesting the medication. He promptly put me on compounded thyroid and I have been as close to perfect as I can get. It truly gave me my life back. To go back to the pills would destroy my lifestyle. At the present I take three compounded drugs due to my stomach surgery and all work as prescribed. Regular pills did not do the job.