I was postmenopausal and was having problems in every facet of my life. Sleeping, sex, emotions, hair loss, dry skin, depression and hot flashes. My husband made an appointment with my gynecologist for me. Had blood tests and my hormones were compounded for exactly what I needed. At first I was tested once a month and then three months and then six months until I had the dosage perfect. I couldn't have survived through this period without these hormones. I was diagnosed with breast cancer. Pathology reported it was not hormonal related. At that time I opted to only stay with progesterone and thyroid. Now both of those are tailor made for exactly what my body needs. I wouldn't sleep and have to resort to sleeping medication without the progesterone.