I was first began hormone replacement during menopause, to balance my metabolism and give me a better quality of life. Now, post menopause, hormone replacement has had the greatest positive impact on my osteoporosis and hypertension of all the therapies I have tried, including weight training. In addition to helping reduce my bone loss, it has returned me to a balanced metabolism and emotional state; a high quality life. I have suffered no negative symptoms from any medication in all the years that I have used hormone replacement.