I was 60 when I began compounded hormones. I was experiencing many symptoms of aging and compounded hormones were recommended. One time I went off the compound and just forgot to start it back up. After about 5 days, I started to experience brain fog, terrible forgetfulness, and lethargy. I did realize it was the fact that I was off the hormones and my symptoms. I was beginning to worry I might have dementia. At some point, after about a month I realized I had not been using my estradiol cream. My pharmacist confirmed my symptoms were due to discontinued use of compound cream. I started back up and the symptoms went away. I sleep so much better due to my compounds. I pray you don't take this away from us. You will have some very upset women out there.