I started when I was perimenopausal and took it all the way through menopause and beyond. I had the easiest menopause in history. I never had a single hot flash. I only had mood swings when I ran out of my Rx. I continue to use it because my MD tells me it is the single best thing I can do for my bone health to combat the osteoporosis. I've been hoping insurance would start to cover this after so many years and so much success. I am APPALLED that the FDA is considering banning this highly helpful NATURAL treatment that every adult should be using and will need at some point in their life.