I started using this over 15 years ago at the advice of a friend who had been using it for many years. I consulted my OBGYN and was given the bioidentical hormone cream which I have used since then. Even though I have changed GYN's twice, I am still on the BHRT. I am now 68 and I am so grateful that I was given this information so early on after experiencing menopause (age 48!). The cream has made a lot of difference in my life quality and health and I would never consider stopping it. I hope the FDA doesn't get this restricted - so many I know have been helped by it as I have passed along that information!