I started taking compounded hormones 15 years ago post-hysterectomy (ovaries intact), when estrogen levels were essentially depleted. I should have the choice of taking a compounded hormone as opposed to synthetic hormones. My prescription for compounded hormones has been adjusted once in 15 years, as they have kept my estrogen levels beautifully stable. To not have my compounded hormone would present a major QOL issue. My compounded hormones are essential to my well-being.