I started going through menopause early and could not tolerate synthetic hormones. They made mevery sick. I finally came across BHRT and it saved my life. I can tolerate it. I take prog caps, test and biest cream, and I have been on this for many years. I cannot go without it. Many women suffer with menopause symptoms that are horrible. Women should not have to suffer like this and be depressed when there is an alternative like biodentical hormone replacement. God bless this therapy.