I started cBHT when I was pre-menopausal and struggling with PMS and PMDD and am now gratefully receiving cBHT during menopause. It has radically changed my life for the better! I feel more "myself" and able to function as a result of cBHT. How do I know? I had to go off of cBHT for a time to deal with another health issue, and it was scary for me and my husband. The chemical fluctuations in the brain that distort reality and cause severe mood swings, secondary to hot flashes/night sweats and insomnia are painful and embarrassing. Without cBHT, my waning hormones dictated my life and made me a prisoner of pain. With cBHT, I have a happy, healthy marriage and I am contributing to society through my work, and caring for family and friends with the energy I have left over. On a final note, personalized dosing also significantly contributes to the success of cBHT. It is notable when a dose is too high or low. I know I would suffer with a synthetic, one-size-attempts-to-fit-all substitute. Compounded, personalized, natural hormone replacement is the only appropriate and ethical option for many women the world over.