Hormone replacement therapy (pellets and compounded progesterone) helped me tremendously. I was only expecting to, hopefully, get back my libido, lessen the brain fog and hope my irritability would go away. Not only did it help all of these but I also had less muscle and joint pain. (the joint pain would keep me awake and night). I got better sleep, my mood improved and I was more energetic. I have been on them for 4 years now and still doing good. I can tell when the pellets is wearing off becasue some of the symptoms start up again. This has been a game changer and to take them away from us would be cruel. It has given me hope and a much better outlook on life.