I have severe vaginal dryness from perimenopause. The problems arose very early in perimenopause and have worsened over the last 10 years. My OBGYN prescribed estrogen cream which I have been using for 10 years now. It has literally saved my relationship. Before the cream, sex was so painful it was impossible and my relationship was eroding. This cream helps two people: myself and my partner. I could not function in a healthy loving relationship without the vaginal estrogen cream.