I have had over 13 vaginal surgeries to correct bladder prolapse. My entire pelvic floor is mesh. I tried conventional Estrace (pregnant horse urine). We are not horses. I had a bad reaction and could not use it It is also NOT recommended for lifetime use. Bioidentical hormone therapy is highly recommended for the rest of my life by my surgeon (who is top in his field in Atlanta, Georgia and travels the world to teach), gynecologist, and urologist, so that my tissues do not atrophy and that I do not have life long infections. Without this medication, I feel I would be in a very bad place in life. Because of this medication, I have been able to live a normal life. Not everyone lives under the guidelines of conventional pharmaceuticals. I have had terrible reactions to most pharmaceuticals and I thank God for bioidentical hormone therapy! It is the only medication I take. Please take everyone into consideration. Natural bioidentical, (closest to the body's own natural hormones) is actually better for the body and I pray I will always be able to use my bioidentical hormones. It has been a long road for me. Without it, I do not know what I would do. In a world full of choices, we should ALL have the choice to use what we feel is best for us, and our bodies. We have come too far for this.....