I have great difficulty tolerating pharmaceutical medications. This hormone therapy cream that I have used for almost two decades now has greatly enhanced my quality of life. It is golden! My prescription is as specialized as my individual needs. It gets tweaked frequently so that I can be feeling my absolute best. I am not opposed to pharmaceutical medications; my husband works for a pharmaceutical company, however there is also a great need for this compounded hormone therapy. There is not a one size fits all when it comes to hormones. This compounded therapy allows an individual approach. I am the ONLY one that is on my prescription dose! That is how specialized it is and how very necessary this compounded hormone therapy is! My life quality would definitely not be the same without it.