I have been using compounded hormone therapy for more than 20 years. I suffer from night sweats and hot flashes. I have tried, unsuccessfully, over the years to do without it in the hopes my body would adjust. It hasn't. Without taking bhrt I awaken pretty much hourly, drenched and awake. Besides being horribly uncomfortable, it is well known that sleep deprivation can cause many maladies, especially at my age of nearly 70. I use bhrt intentionally and instead of synthetic hormones. I have never had negative issues with the use of compounded bhrt, only positive ones. I would be completely lost and miserable without access to these sanity saving compounded bioidentical hormones.