I have been using cBHT since 2012 when I had problems with Premarin, managing the symptoms of menopause. I had a complete hysterectomy at age 39 (I am 64) and have needed hormone replacement since that time. I have found the troche to manage severe menopause symptoms since that time. I did not have success with creams. I have completed regular labs since beginning cBHT and worked to minimize my dosage to the lowest level that are able to be beneficial - as measured by symptom relief. I have medical providers in my family and have read Estrogen Matters by Bluming & Tarvis to be informed of the history and research related to hormone replacement given my unique history, family factors, etc. Please, please be mindful of the research outlined in Estrogen Matters which is different from what many physicians are operating from. And please provide approval of this meaningful treatment for over half of the population.