I have been using bioidentical hormone replacement for 16 years now. My formulas are tailor made for me. Only what I need to replace and keep in balance. I have had no adverse effects and am very pleased with my compounded medications. I did not want to use a one size fits all drug made for the masses. Please don't let Big Pharma have their way and discontinue the compounded medications that have been a big part of my health and well being. I am 66 years old and very active. I feel great. Thank you.