I have been using bioidentical compounded hormones for 20 years. I began them right before my hysterotomy and after. My symptoms were debilitating. Different doctors put me on synthetic hormones and they did not help. I felt awful all the time. If I do not take them regularly I begin to have problems again: anxiety, extreme fatigue, and insomnia. It shows up in my hormone labs and affects my thyroid labs. They have greatly improved my quality of life. I cannot imagine not having them. The thought of not having it is disturbing. My body is very sensitive to medications. Without it, I would be left with no options.