I have been using a blend of Estriol and Progesterone for many years and I believe it's why I am healthy and have decent bone health at age 73. I believe HRT can be damaging because the estrogen utilized can be cancer producing. By compounding estriol instead of all three of the estrogens with Progesterone is mild enough to use for many years. Why would this be restricted? I pay out of pocket for it since it's never been covered and this is a choice I have made. I receive regular check-ups.