I have been prescribing bioidentical hormones (cBHT) to my patients for 27 years. Many of my patients do not tolerate synthetic hormones, or do not tolerate the inert ingredients in hormone creams like premarin or estrace cream. I have also seen that patients who take hormones as creams tolerate them much better than when taken orally. Often I have to adjust doses of hormones that I prescribe on a regular basis and conventional hormone therapies do not allow me the same flexibility that using compounded bioidentical hormones do.