I have a genetic thyroid problem that can cause considerable difficulty for me. Menopause was very difficult. In taking the bioidentical hormones, I experienced a great lessening of menopausal symptoms. I have been on them for several years with no difficulties. My life has been very much improved by taking bioidentical hormones. Perhaps the FDA would benefit by asking individuals themselves of their experience with bioidenticals. It sounds as if those companies who create non-bioidentical hormones are beginning to feel threatened that their profits will not be made if individuals switch to bioidenticals or take them instead of the synthetics. Why would anyone want to put something in their body that was not there in the first place. As far as I am concerned, natural is the best way to go.