I had to have a complete hysterectomy in my 30's after much research and trying the conventional hormones (not compounded, which the side affects were not acceptable) I went with the compounded natural hormones which I have been taking under the tongue for many many years with no ill affects and great results, no hot flashes, night sweats, skin color change etc etc. Please please do not take away my hormone replacement therapy. I cannot and will not take the synthetic versions as they are not an option for me.