I had to have a total hysterectomy by the time I was 40. I had severe PCOS and tons of fibroids in my uterus. I went several years with no hornones because the synthetic estradiol pills did nothing for me and there is a strong breast cancer risk. I started having anxiety, mood swings, ringing wet hair, and blew up like s balloon. I thought I was going crazy. These compound hormones saved my life. I don't want to go back to that dark place. Why would they take these? They work so well snd zero side effects.