I had a complete hysterectomy at 27. I used to take estratest pills. I started feeling bad about five years ago. I had blood work done and found out that the pills were doing nothing and not helping at all. I have been on HRT for about four years now and it has saved my life. I can sleep better and don't have sweaty legs at night anymore. I can think better. I am not irritable anymore and don't have hot flashes all day long. I was miserable before. Now I feel like myself again.