I experienced extreme fatigue. Hormone testing showed high estrogen and very low testosterone. With coronary issues in my family I need to protect my heart. With testing every six months, I am able to keep my hormones balanced. My quality of life has improved 100%. I can keep up with my grandchildren and do not experience any fatigue and sleep has improved. Not taking compounded hormones would negatively affect my life and my heart. No other product can be exact enough to keep me balanced. I am thankful for compounding hormones.