I began using compounded BHRT (as a cream) many years ago when I began going through menopause. The positive benefits were noticeable immediately in terms of bone health (osteoporosis prevention), brain health, and cardiovascular health. I have a wonderful pharmacy and I've worked with an excellent Functional Medicine Doctor who has monitored the dosage and positive effects of the therapy over the years. It would be very detrimental to all aspects of my health if I was forced to give up this vital treatment.