I am not the patient, but the husband of the patient and a Certified Registered Nurse Anesthetist. My wife had endured years of insomnia, hot flashes, dyspareunia and mood swings after having to discontinue oral hormones due to breast cancer. She became severely depressed and threatened suicide on more than one occasion. We found a naturopathic physician that was able to diagnose her issues as hormone depletion and she was started on a regimen of transdermal replacement hormone creams that could be finely adjusted through compounding. This allowed her to receive replacement levels that corrected her hormone levels and resolved her symptoms without overshooting her baseline requirement which could potentially feed her breast cancer. I believe compounded hormone replacement saved my wife's life! She has a quality of life today that is as fulfilling as it was prior to her cancer diagnosis and her discontinuation of the oral agents. We are both medical professionals with a combined 90 years of experience as Registered Nurses and Nurse Anesthetists and we can both attest to the incredible efficacy and high margin of safety of the compounded hormones my wife has been prescribed. They have become an integral ingredient in my wife's overall physical health and a huge component of our shared psychological well-being.