I am not a candidate for traditional hormone replacement because my sister has has breast cancer. The cBHT has been a godsend, allowing me to have effective hormone replacement. This has improved my mood, my health, and my bones, as I have osteoporosis now, as well. I must say, this is the third time I have had to do this with the FDA, and I am completely appalled that they won't leave this issue alone. It has made a world of difference in my life.