I am a 55 year old female who is in menopause. During this time I have suffered from extreme fatigue, difficulty concentrating, sleep disturbance and muscular pain. My progesterone was low and my estrogen almost undetectable. I was hesitant torward taking any synthetic hormone replacement at all due to the side effects of breast cancer. In talking to my physician, he had mentioned to me that compounded hormone replacement is a great alternative as it is plant-derived and not synthetic. This was comforting and gave me hope to getting my life back and willing to give it a try. I have been amazingly impressed as everything but the muscular pain has greatly subsided! I feel that my safety comes first and I feel very comfortable continuing this therapy over the course of menopause. The risks of synthetic hormones were enough to scare me and I was willing to suffer in silence. I am extremely grateful to this alternative and many of my friends have done the same! Please do not take compounded hormones away as many of us are neither comfortable or able to take synthetic hormones!