I am 70 years old and have taken cBHT hormones for approximately 20 years. It has prevented maternal osteoporosis, and I have absolutely no bone density loss, and no cardiovascular incidences. I have NOT experienced hot flashes or weight gain in 20 years, depression or mood swings, or vaginal dryness. My husband has Alzheimer's, therefore sexual activity is nonexistant. I have recommended bioidentical hormones to other women. The advantages, to me, greatly outweigh the out of pocket cost.