I started cHRT in my mid 40's. I was perimenopausal suffering from anxiety, panic attacks and depression. I tried HRT pills but they didn't help me. So went onto cHRT. I improved a lot. My therapist even noticed it. In 2018, I thought due to my age I would wean off. I did only to throw myself into severe anxiety, panic, and depression. Lost 20 pounds and muscle. I started seeing a therapist and tried anti-anxiety and antidepressant meds. The anti-anxiety helped some. But I was in a bad place mentally. Living day to day was hard. My husband and family can attest to that about me. I started cHRT back up. And with time, I am back to myself again. Please don't take away cHRT. I can't do that again. I may not make it.