I had to have a complete hysterectomy in my 40's. With my ovaries gone I was not producing estrogen. I ignorantly thought I wouldn't need to replace it. The change was rapid and overwhelming. I became depressed & had no energy. I could barely get out of bed. The difference after I started the bio-identical compounded hormone cream was night & day. They brought me back to life. I can't overstate their necessity and benefit. Please recognize the absolute need for this therapy. Thank you!!