I am a 76-year-old woman. I have been using bio-identical hormone replacement therapy since 1996. Without it, my estrogen level is far below the minimum for functionality. If I take the prescription Estrogen, I don't get the 2 estrogens I need without the third estrogen, which I test very high for. Every year I am tested to see the exact amount of each of the estrogens, progesterone, and if needed testosterone, that my body requires. My vagina is starting to atrophy, and the only solution that is purely what I need and nothing else is a compounded estrogen gel to use twice a week. No patch or prescription can individualize the hormones I need to avoid depression, brain fog, sexual dysfunction, or good quality of life. Thanks for reading my story.