After my complete hysterectomy I had horrible hormonal issues. I tried the patches, pills, creams, gels, most every brand which was very frustrating. My body does not like foreign chemicals, additives, etc and in return makes me feel worse. Not until my Nurse Practitioner prescribed compounded hormones for me did things start to improve, so life began to become joyful again. What was even better was my insurance at that time BCBS paid for my compounded hormones so wasn’t a burden on our finances. Now that has changed so I pay almost $200 out of pocket just to feel normal, so my life would be miserable again if there was no compounded medicines. I also take a compounded Thyroid which is great also.