In my early thirties, my uterus and ovaries were removed due to severe disease. I was prescribed synthetic hormones immediately and for ten years I rode a roller coaster of moods and felt terrible. I could not synthesize them and the Premarin and other equine hormones put me in instant menopause with hot flashes, mood swings, and feeling terrible ALL the time. When bioidentical hormones came along, my life changed. My body could use them. I absolutely have to have compounded hormones to feel balanced and healthy. My doctors have come up with just what is right for me. Please do not even consider making compounded hormones any harder to get!! I am not asking, I am imploring you to keep compounded bio-identical hormones available!!