I started compounded BHRT at the age of 50 however I am positive I needed it around age of 40. I was depressed, had severe hip pain, hot flashes, headaches, full-body aches, no sexual desire, exhausted, overweight, and pre-diabetic with an overall feeling of helplessness and full-body pain. I started compounded BHRT and within 3 months all negative symptoms were GONE! Also, my fibrous breast tissue returned to normal. I am not sure I would even be alive without this treatment. It saved my life.