I am Estrogen dominant. Five years ago I was having trouble managing my energy, cognitive ability, sleep, and anxiety. I asked my OBGYN for a Progesterone supplement. She prescribed the standard pharmaceutical Prometrium. I had horrible side effects from this poisonous synthetic drug; headaches, drowsiness, nightmares, vision problems, mood changes, depression, and dizziness. I stopped taking Prometrium and read about alternatives to Progesterone, such as creams. I tried creams but did not like that I was not completely in control of the dosage. I read more and found out about compounded bio-identical hormone therapy (cBHT) for Progesterone. It has changed my life. I have been taking 100mg of compounded bio-identical Progesterone for almost four years. It has solved my energy, cognitive, sleep and anxiety issues. In addition it has balanced my high Estrogen, preventing me from cancers and calming my endometriosis. Recently, I developed Mast Cell Activation Syndrome from a bout of severe allergies. The cBHT Progesterone blocks Mast Cell secretion (https://journals.sagepub.com/doi/pdf/10.1177/039463200601900408) and has helped calm down my histamine attacks. I just renewed my prescription for 200mg daily dose. I can not stress how much this cBHT Progestrone has saved my life and I don’t know what I would do without it. I certainly hope the FDA does not take this away from women. It would be a catastrophic tragedy to many women like myself, I’m certain.